cdk9 inhibitor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T118066	CDK9 inhibitor HH1	8019-9719	CDK
	CDK9 inhibitor HH1 (8019-9719) is an inhibitor of the human CDK2-cyclin A2 complex with an IC50 value of 2 μM.		CDK
T16363	NVP-2		Apoptosis , CDK
	NVP-2 is an effective and selective ATP-competitive cyclin-dependent kinase 9 (CDK9) probe. NVP-2 induces cell apoptosis. NVP-2 inhibits CDK9/CycT activity (IC50: 0.514 nM). NVP-2 shows inhibitory effcts on CDK1/CycB, CD...		Apoptosis , CDK
T10096L	Voruciclib		CDK
	Voruciclib is an orally active and selective CDK inhibitor (Ki: 0.626 nM-9.1 nM). Voruciclib represses the expression of MCL-1 in multiple models of diffuse large B-cell lymphoma. Voruciclib effectively blocks CDK9, the ...		CDK
T14918	CDK9-IN-2		Others , CDK
	CDK9-IN-2 is a special CDK9 inhibitor and has an IC50 of 5 nM and 7 nM in A2058 skin cell line (72 hours) and H929 multiple myeloma cell line (72 hours), respectively.		Others , CDK
T9615	CK7		CDK
	CK7, a Cdk2/9 inhibitor, is instrumental in the synthesis of Nek1 inhibitors BSc5231 and BSc5367.		CDK
T5438	PROTAC CDK9 Degrader-1		CDK
	PROTAC CDK9 Degrader-1 is a selective CDK9 degrader.		CDK
T9446	KB-0742 dihydrochloride		CDK
	KB-0742 dihydrochloride is a potent, selective and orally inhibitor of CDK9.		CDK
T8972	FIT-039		Others , DNA/RNA Synthesis , CDK , HSV
	FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a pr...		Others , DNA/RNA Synthesis , CDK , HSV
T17143	Toyocamycin	Vengicide	Apoptosis , Others , IRE1 , Antibiotic , Antifungal
	Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage (IC50: 80 nM). Toyocamycin induces apoptosis.		Apoptosis , Others , IRE1 , Antibiotic , Antifungal
T10746	CDK9-IN-8		CDK
	CDK9-IN-8 is a highly potent and selective CDK9 inhibitor (IC50: 12 nM).		CDK
T10742	CDK9-IN-10		CDK
	CDK9-IN-10 is a potent CDK9 inhibitor and the ligand for the PROTAC CDK9 degrader-2.		CDK
TQ0078	CDK-IN-2	CDK inhibitor II	CDK
	CDK-IN-2 (CDK inhibitor II) is a potent and specific CDK9 inhibitor (IC50: <8 nM).		CDK
T70388L	(R)-Enitociclib		CDK
	(R)-Enitociclib, an enantiomer of BAY-1251152, is a CDK9 inhibitor with anticancer activity.		CDK
T8484	JSH-150		CDK
	JSH-150 is a highly selective CDK9 inhibitor(IC50 : 1 nM).		CDK
T10464L	Atuveciclib Racemate	BAY-1143572 Racemate	CDK
	Atuveciclib Racemate (BAY-1143572 Racemate) is the racemate mixture of Atuveciclib, which is a potent and highly selective, oral P-TEFb/CDK9 inhibitor which supresses CDK9/CycT1 with an IC50 of 13 nM.		CDK
T6563	LDC000067	LDC067	Apoptosis , CDK
	LDC000067 (LDC067) is a highly specific and selective CDK9 inhibitor with an IC50 value of 44±10 nM.		Apoptosis , CDK
T8796	CAN508		CDK
	CAN508 is a potent, ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 μM. It is also a competitive inhibitor of Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 and 20 μM, respectively.CAN50...		CDK
T60619	CDK9-IN-15		CDK
	CDK9-IN-15 is a potent small molecule CDK9 inhibitor, which can block the phosphorylation of positive transcription elongation factor b (P-TEFb) on the C-terminal region of RNA Poly-II by degradation and inhibition of CD...		CDK
T6206	PHA-767491	CAY10572,PHA767491,PHA 767491	cholecystokinin , GSK-3 , CDK
	PHA-767491 (CAY10572) is a potent ATP-competitive dual Cdc7/CDK9 inhibitor with IC50 of 10 nM and 34 nM, respectively.		cholecystokinin , GSK-3 , CDK
T60152	AZ5576		CDK
	AZ5576 is a potent and highly selective CDK9 inhibitor. AZ5576 can be used for the research of Hematological Malignancy [1].		CDK